Nthl1 | nth (endonuclease III)-like 1 (E.coli)

GeneMGI:1313275Synonyms: Nth1

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Liver/biliary system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vitreous body morphology	1 supporting dataset	Nthl1^em1(IMPC)Mbp	homozygote	Early adult	6.32x10^-6
cataract	1 supporting dataset	Nthl1^em1(IMPC)Mbp	homozygote	Early adult	7.74x10^-6
abnormal liver morphology	1 supporting dataset	Nthl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small liver	1 supporting dataset	Nthl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nthl1.

Associated images

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Histopathology

There is no histopathology data found for Nthl1.

IMPC related publications

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External links

No external links available for Nthl1.

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*Nthl1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Nthl1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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