Sptbn2 | spectrin beta, non-erythrocytic 2

GeneMGI:1313261Synonyms: Spnb3

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Hematopoietic system Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

4Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Sptbn2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.08x10^-6
increased circulating phosphate level	1 supporting dataset	Sptbn2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.23x10^-5
decreased hemoglobin content	1 supporting dataset	Sptbn2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.53x10^-5
increased circulating creatine kinase level	1 supporting dataset	Sptbn2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.33x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sptbn2.

Associated images

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Histopathology

There is no histopathology data found for Sptbn2.

IMPC related publications

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External links

No external links available for Sptbn2.

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*Sptbn2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Sptbn2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sptbn2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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