Tagln2 | transgelin 2

GeneMGI:1312985Synonyms: 2700094C18Rik, Sm22B

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased neutrophil cell number	2 supporting datasets	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	1.28x10^-8
increased vertical activity	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	6.91x10^-5
abnormal sternum morphology	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	1.4x10^-6
increased mean platelet volume	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	8.06x10^-5
decreased lymphocyte cell number	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	1.37x10^-7
shortened QRS complex duration	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	6.48x10^-5
abnormal skin morphology	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Tagln2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tagln2.

Associated images

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Histopathology

There is no histopathology data found for Tagln2.

IMPC related publications

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External links

No external links available for Tagln2.

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*Tagln2^em1(IMPC)Tcp*	Deletion	‌	mouse
*Tagln2^tm1aNarl*	KO first allele (reporter-tagged insertion with conditional potential)	‌	ES Cell
*Tagln2^{tm234328(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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