Cdc7 | cell division cycle 7
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Integument Hematopoietic system Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
increased lymphocyte cell number | 1 supporting dataset | Cdc7tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.55x10-6 | ||
decreased neutrophil cell number | 1 supporting dataset | Cdc7tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.32x10-5 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Cdc7tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Cdc7tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Cdc7tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
abnormal skin morphology | 1 supporting dataset | Cdc7tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
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External links
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Cdc7tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Cdc7tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Cdc7tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cdc7tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Cdc7tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cdc7tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |