Cdc7 | cell division cycle 7

GeneMGI:1309511Synonyms: Cdc7, muCdc7, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Integument Hematopoietic system Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues

Phenotypes

increased lymphocyte cell number1 supporting datasetCdc7tm1.1(KOMP)VlcgheterozygoteEarly adult2.55x10-6 
decreased neutrophil cell number1 supporting datasetCdc7tm1.1(KOMP)VlcgheterozygoteEarly adult1.32x10-5 
embryonic lethality prior to organogenesis1 supporting datasetCdc7tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetCdc7tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetCdc7tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetCdc7tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdc7tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Cdc7tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Cdc7tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdc7tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Cdc7tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdc7tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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