Pcdh9 | protocadherin 9

GeneMGI:1306801Synonyms: 1500001L12Rik, C530050I23Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetPcdh9tm1.1(KOMP)VlcgheterozygoteEarly adult4.94x10-10 
hyperactivity9 supporting datasetsPcdh9tm1.1(KOMP)VlcgheterozygoteEarly adult1.13x10-18 
decreased grip strength4 supporting datasetsPcdh9tm1.1(KOMP)VlcgheterozygoteEarly adult2.64x10-7 
increased circulating aspartate transaminase level1 supporting datasetPcdh9tm1.1(KOMP)VlcgheterozygoteEarly adult9.6x10-6 
increased circulating bilirubin level1 supporting datasetPcdh9tm1.1(KOMP)VlcgheterozygoteEarly adult1.2x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetPcdh9tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating phosphate level1 supporting datasetPcdh9tm1.1(KOMP)VlcgheterozygoteEarly adult6.12x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pcdh9tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Pcdh9tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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