Cabin1 | calcineurin binding protein 1

GeneMGI:1298375Synonyms: Ppp3in, Cain, +1 more

Physiological systems

23 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Respiratory system Hematopoietic system Cardiovascular system Mortality/aging

16 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal thymus morphology1 supporting datasetCabin1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetCabin1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
decreased lung elastance1 supporting datasetCabin1em1(IMPC)CcpczheterozygoteEarly adult2.41x10-5 
enlarged thymus1 supporting datasetCabin1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged heart1 supporting datasetCabin1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetCabin1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cabin1em1(IMPC)CcpczExon Deletionmouse
Cabin1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell

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