Pip5k1c | phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging
17 No significant impact
3 Not tested
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:55Adult tissues
50Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Pip5k1ctm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Pip5k1ctm1b(KOMP)Wtsi | heterozygote | Early adult | 4.11x10-7 | ||
| edema | 1 supporting dataset | Pip5k1ctm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Pip5k1ctm1b(KOMP)Wtsi | heterozygote | Early adult | 1.02x10-5 | ||
| decreased grip strength | 1 supporting dataset | Pip5k1ctm1b(KOMP)Wtsi | heterozygote | Early adult | 4.02x10-5 |
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External links
No external links available for Pip5k1c.
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| Pip5k1ctm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pip5k1ctm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |