Sf3b3 | splicing factor 3b, subunit 3
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Pigmentation Integument Vision/eye Behavior/neurological Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal vocalization | 1 supporting dataset | Sf3b3em1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| abnormal cornea morphology | 1 supporting dataset | Sf3b3em1(IMPC)J | heterozygote | Early adult | 2.3x10-5 | ||
| decreased thigmotaxis | 2 supporting datasets | Sf3b3em1(IMPC)J | heterozygote | Early adult | 1.13x10-5 | ||
| hyperactivity | 1 supporting dataset | Sf3b3em1(IMPC)J | heterozygote | Early adult | 7.2x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Sf3b3em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sf3b3em1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal behavior | 1 supporting dataset | Sf3b3em1(IMPC)J | heterozygote | Early adult | 1.13x10-5 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Sf3b3em1(IMPC)J | heterozygote | Early adult | 6.5x10-12 |
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External links
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| Sf3b3em1(IMPC)J | Exon Deletion | | mouse |
| Sf3b3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sf3b3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |