Pxk | PX domain containing serine/threonine kinase
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Adipose tissue Growth/size/body region Hematopoietic system Skeleton
11 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased bone mineral content | 1 supporting dataset | Pxkem1(IMPC)Tcp | homozygote | Early adult | 2.62x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Pxkem1(IMPC)Tcp | homozygote | Early adult | 4.69x10-6 | ||
| abnormal skin morphology | 1 supporting dataset | Pxkem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Pxkem1(IMPC)Tcp | homozygote | Early adult | 2.28x10-11 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Pxkem1(IMPC)Tcp | homozygote | Early adult | 4.26x10-6 | ||
| decreased lean body mass | 1 supporting dataset | Pxkem1(IMPC)Tcp | homozygote | Early adult | 2.32x10-6 |
| | | | | | | | | | |
External links
No external links available for Pxk.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Pxkem1(IMPC)Tcp | Exon Deletion | | mouse |
| Pxktm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pxktm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |