Ncaph2 | non-SMC condensin II complex, subunit H2

GeneMGI:1289164Synonyms: 2610524G04Rik, Kleisin beta, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetNcaph2tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal glucose homeostasis1 supporting datasetNcaph2tm1a(EUCOMM)WtsiheterozygoteEarly adult4.87x10-5 
increased circulating amylase level1 supporting datasetNcaph2tm1a(EUCOMM)WtsiheterozygoteEarly adult6.62x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ncaph2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ncaph2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ncaph2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ncaph2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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