Mpzl2 | myelin protein zero-like 2

GeneMGI:1289160Synonyms: Eva, Eva1

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Pigmentation Integument Adipose tissue Limbs/digits/tail Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



long tibia	1 supporting dataset	Mpzl2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.21x10^-8
abnormal gait	1 supporting dataset	Mpzl2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.91x10^-5
increased total body fat amount	2 supporting datasets	Mpzl2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.5x10^-6
abnormal coat/hair pigmentation	1 supporting dataset	Mpzl2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.76x10^-5
abnormal ear morphology	1 supporting dataset	Mpzl2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.49x10^-5
increased red blood cell distribution width	1 supporting dataset	Mpzl2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.7x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mpzl2.

Associated images

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Histopathology

There is no histopathology data found for Mpzl2.

IMPC related publications

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External links

No external links available for Mpzl2.

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*Mpzl2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mpzl2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mpzl2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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