Pcm1 | pericentriolar material 1

GeneMGI:1277958Synonyms: 2600002H09Rik, C030044G17Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Pigmentation Integument Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Craniofacial

5 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	6.53x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	3.86x10^-5
decreased prepulse inhibition	4 supporting datasets	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	2.27x10^-6
hydrocephaly	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	1.69x10^-18
prolonged QRS complex duration	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	1.84x10^-6
impaired glucose tolerance	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	7.21x10^-6
prolonged RR interval	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	9.07x10^-5
male infertility	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased startle reflex	1 supporting dataset	Pcm1^em1(IMPC)Tcp	homozygote	Early adult	6.09x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pcm1.

Associated images

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Histopathology

There is no histopathology data found for Pcm1.

IMPC related publications

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External links

No external links available for Pcm1.

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*Pcm1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Pcm1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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