Pycr2 | pyrroline-5-carboxylate reductase family, member 2

GeneMGI:1277956Synonyms: P5cr2, 1810018M05Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



limb grasping	1 supporting dataset	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.78x10^-19
decreased bone mineral density	1 supporting dataset	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.93x10^-6
increased fasting circulating glucose level	1 supporting dataset	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.59x10^-5
decreased monocyte cell number	4 supporting datasets	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased Ly6C low monocyte number	2 supporting datasets	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
absent pinna reflex	1 supporting dataset	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.03x10^-13
trunk curl	1 supporting dataset	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.26x10^-10
increased mean corpuscular hemoglobin	1 supporting dataset	Pycr2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.3x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pycr2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pycr2.

IMPC related publications

Loading...

External links

No external links available for Pycr2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pycr2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Pycr2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes