Rpap3 | RNA polymerase II associated protein 3

GeneMGI:1277218Synonyms: D15Ertd682e, 2310042P20Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Rpap3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased circulating glucose level	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	2.43x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Rpap3^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
enlarged thymus	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
decreased circulating phosphate level	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	2.38x10^-5
decreased circulating calcium level	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	5.17x10^-7
abnormal thymus morphology	1 supporting dataset	Rpap3^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rpap3.

Associated images

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Histopathology

There is no histopathology data found for Rpap3.

IMPC related publications

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External links

No external links available for Rpap3.

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*Rpap3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rpap3^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rpap3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rpap3^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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