Bbs1 | Bardet-Biedl syndrome 1
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Vision/eye Mortality/aging Cardiovascular system
17 No significant impact
2 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal placenta vasculature | 1 supporting dataset | Bbs1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal blood vessel morphology | 1 supporting dataset | Bbs1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Bbs1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Bbs1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Bbs1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Bbs1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Bbs1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Bbs1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Bbs1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Bbs1em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
No external links available for Bbs1.
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| Bbs1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Bbs1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Bbs1tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |