Septin11 | septin 11

GeneMGI:1277214Synonyms: Sept11, 6230410I01Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Embryo Growth/size/body region Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsSeptin11em1(IMPC)TcphomozygoteEarly adultN/A * 
embryonic growth retardation1 supporting datasetSeptin11em1(IMPC)TcphomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetSeptin11em1(IMPC)TcphomozygoteE12.5N/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetSeptin11em1(IMPC)TcphomozygoteE15.5N/A * 
abnormal embryo size1 supporting datasetSeptin11em1(IMPC)TcphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Septin11em1(IMPC)TcpExon Deletionmouse
Septin11tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Septin11tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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