Macir | macrophage immunometabolism regulator
Physiological systems
21 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
19 No significant impact
3 Not tested
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
49Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Macirtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Macirtm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.01x10-5 | ||
| increased circulating potassium level | 1 supporting dataset | Macirtm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.28x10-7 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Macirtm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.88x10-5 | ||
| increased circulating sodium level | 1 supporting dataset | Macirtm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.04x10-5 | ||
| increased circulating chloride level | 1 supporting dataset | Macirtm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.67x10-5 |
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External links
No external links available for Macir.
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| Macirtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Macirtm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Macirtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Macirtm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |