Tmem42 | transmembrane protein 42

GeneMGI:1277176Synonyms: 4933429E06Rik, D9Ertd662e, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating HDL cholesterol level	1 supporting dataset	Tmem42^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.89x10^-5
increased bone mineral density	1 supporting dataset	Tmem42^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.68x10^-6
increased lean body mass	1 supporting dataset	Tmem42^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.42x10^-5
increased bone mineral content	1 supporting dataset	Tmem42^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.94x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem42.

Associated images

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Histopathology

There is no histopathology data found for Tmem42.

IMPC related publications

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External links

No external links available for Tmem42.

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*Tmem42^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmem42^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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