Snca | synuclein, alpha
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system
13 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean platelet volume | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Late adult | 2.5x10-5 | ||
| increased spleen weight | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Late adult | 1.42x10-20 | ||
| increased circulating creatinine level | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Late adult | 9.85x10-9 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Early adult | 6.46x10-5 | ||
| abnormal locomotor behavior | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Early adult | 4.06x10-5 | ||
| prolonged PR interval | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Late adult | 9.8x10-5 | ||
| increased circulating amylase level | 1 supporting dataset | Sncaem1(IMPC)H | homozygote | Late adult | 1.59x10-5 |
| | | | | | | | | | |
External links
No external links available for Snca.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Sncaem1(IMPC)H | Exon Deletion | | mouse |
| Sncaem2(IMPC)H | Exon Deletion | | mouse |
| Sncatm364452(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |