Ldlrad4 | low density lipoprotein receptor class A domain containing 4

GeneMGI:1277150Synonyms: D18Ertd653e, 8230401C20Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased monocyte cell number	1 supporting dataset	Ldlrad4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Ldlrad4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.37x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ldlrad4.

Associated images

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Histopathology

There is no histopathology data found for Ldlrad4.

IMPC related publications

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External links

No external links available for Ldlrad4.

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*Ldlrad4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ldlrad4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ldlrad4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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