Ptp4a2 | protein tyrosine phosphatase 4a2

GeneMGI:1277117Synonyms: Prl-2

Physiological systems

19 / 24 physiological systems tested

13 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Digestive/alimentary Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

6 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



thick skin	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	1.32x10^-27
decreased lean body mass	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	3.88x10^-6
small testis	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	3 supporting datasets	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	2.19x10^-7
abnormal bone structure	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	1.24x10^-5
enlarged lymph nodes	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	9.91x10^-7
increased total body fat amount	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	1.4x10^-6
abnormal skin morphology	1 supporting dataset	Ptp4a2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptp4a2.

Associated images

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Histopathology

There is no histopathology data found for Ptp4a2.

IMPC related publications

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External links

No external links available for Ptp4a2.

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*Ptp4a2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Ptp4a2^{tm88149(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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