Pde8a | phosphodiesterase 8A

GeneMGI:1277116Synonyms: Pde8

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	2 supporting datasets	Pde8a^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.32x10^-9
increased total body fat amount	2 supporting datasets	Pde8a^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.54x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pde8a.

Associated images

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Histopathology

There is no histopathology data found for Pde8a.

IMPC related publications

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External links

No external links available for Pde8a.

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*Pde8a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	es cell mouse
*Pde8a^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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