Pacs1 | phosphofurin acidic cluster sorting protein 1

GeneMGI:1277113

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Pacs1^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Pacs1^{em1(IMPC)Hmgu}	heterozygote	Early adult	N/A ^*
increased circulating lipase level	1 supporting dataset	Pacs1^{em1(IMPC)Hmgu}	heterozygote	Early adult	9.11x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pacs1.

Associated images

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Histopathology

There is no histopathology data found for Pacs1.

IMPC related publications

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External links

No external links available for Pacs1.

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*Pacs1^{em1(IMPC)Hmgu}*	Intra-exon deletion	‌	mouse
*Pacs1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pacs1^{tm184482(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes