Birc6 | baculoviral IAP repeat-containing 6

GeneMGI:1276108Synonyms: apollon, A430032G04Rik, +3 more

Physiological systems

23 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

17 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal heart morphology1 supporting datasetBirc6em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged heart1 supporting datasetBirc6em1(IMPC)CcpczheterozygoteEarly adultN/A * 
increased circulating creatine kinase level1 supporting datasetBirc6em1(IMPC)CcpczheterozygoteEarly adult4.38x10-7 
preweaning lethality, complete penetrance1 supporting datasetBirc6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
no spontaneous movement1 supporting datasetBirc6em1(IMPC)CcpczhomozygoteE18.5N/A * 
abnormal retina morphology1 supporting datasetBirc6em1(IMPC)CcpczheterozygoteEarly adult4.66x10-8 
edema1 supporting datasetBirc6em1(IMPC)CcpczhomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Birc6em1(IMPC)CcpczExon Deletionmouse

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