Mmp16 | matrix metallopeptidase 16

GeneMGI:1276107Synonyms: MT3-MMP, Membrane type 3-MMP

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



hyperactivity	8 supporting datasets	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.28x10^-13
abnormal eye morphology	1 supporting dataset	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
hypoalgesia	1 supporting dataset	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.21x10^-6 ^**
decreased anxiety-related response	1 supporting dataset	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.4x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

** Significant with a threshold of 1x10^-3, check the Pain Sensitivity page for more information.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

** Significant with a threshold of 1x10^-3, check the Pain Sensitivity page for more information.

Download data as:

lacZ Expression

No adult expression data available for Mmp16.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mmp16.

IMPC related publications

Loading...

External links

No external links available for Mmp16.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mmp16^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mmp16^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mmp16^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mmp16^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes