Mmp16 | matrix metallopeptidase 16

GeneMGI:1276107Synonyms: MT3-MMP, Membrane type 3-MMP

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



hyperactivity	8 supporting datasets	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.28x10^-13
abnormal eye morphology	1 supporting dataset	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
hypoalgesia	1 supporting dataset	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.21x10^-6 ^**
decreased anxiety-related response	1 supporting dataset	Mmp16^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.4x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

** Significant with a threshold of 1x10^-3, check the Pain Sensitivity page for more information.

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* This parameter was manually assessed for significance.

** Significant with a threshold of 1x10^-3, check the Pain Sensitivity page for more information.

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lacZ Expression

No adult expression data available for Mmp16.

Associated images

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Histopathology

There is no histopathology data found for Mmp16.

IMPC related publications

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External links

No external links available for Mmp16.

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*Mmp16^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mmp16^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mmp16^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Mmp16^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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