Adgrv1 | adhesion G protein-coupled receptor V1

GeneMGI:1274784Synonyms: Gpr98, Mass1, +2 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Limbs/digits/tail Nervous system Hearing/vestibular/ear Behavior/neurological Skeleton

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

4Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal startle reflex	1 supporting dataset	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.07x10^-8
decreased prepulse inhibition	4 supporting datasets	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.19x10^-21
abnormal auditory brainstem response	6 supporting datasets	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.22x10^-6
abnormal testis morphology	1 supporting dataset	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
short tibia	1 supporting dataset	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.65x10^-5
small testis	1 supporting dataset	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased startle reflex	1 supporting dataset	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.01x10^-5
hyperactivity	1 supporting dataset	Adgrv1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.2x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adgrv1.

Associated images

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Histopathology

There is no histopathology data found for Adgrv1.

IMPC related publications

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External links

No external links available for Adgrv1.

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*Adgrv1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Adgrv1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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