Robo1 | roundabout guidance receptor 1
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Embryo Behavior/neurological Mortality/aging
19 No significant impact
2 Not tested
Data collections
Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| no spontaneous movement | 1 supporting dataset | Robo1em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| abnormal behavior | 1 supporting dataset | Robo1em1(IMPC)Mbp | heterozygote | Early adult | 8.8x10-7 | ||
| decreased anxiety-related response | 1 supporting dataset | Robo1em1(IMPC)Mbp | heterozygote | Early adult | 3.65x10-5 | ||
| decreased thigmotaxis | 2 supporting datasets | Robo1em1(IMPC)Mbp | heterozygote | Early adult | 7.83x10-7 | ||
| abnormal placenta morphology | 1 supporting dataset | Robo1em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Robo1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Robo1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Robo1em1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Robo1em1(IMPC)Mbp | heterozygote | Early adult | 6.1x10-6 |
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External links
No external links available for Robo1.
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| Robo1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Robo1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Robo1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |