Slc6a2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| small heart | 1 supporting dataset | Slc6a2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal gait | 1 supporting dataset | Slc6a2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.24x10-7 | ||
| decreased hemoglobin content | 1 supporting dataset | Slc6a2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.7x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Slc6a2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| impaired glucose tolerance | 1 supporting dataset | Slc6a2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.81x10-6 |
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External links
No external links available for Slc6a2.
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| Slc6a2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Slc6a2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Slc6a2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |