Wwc2 | WW, C2 and coiled-coil domain containing 2
Physiological systems
16 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Reproductive system Skeleton Mortality/aging
13 No significant impact
8 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased bone mineral content | 1 supporting dataset | Wwc2em1(IMPC)Bay | heterozygote | Early adult | 9.19x10-5 | ||
| abnormal bone structure | 1 supporting dataset | Wwc2em1(IMPC)Bay | heterozygote | Early adult | 5.65x10-6 | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Wwc2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Wwc2em1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
| male infertility | 1 supporting dataset | Wwc2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Wwc2em1(IMPC)Bay | homozygote | Early adult | N/A * |
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External links
No external links available for Wwc2.
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| Wwc2em1(IMPC)Bay | Exon Deletion | | mouse |
| Wwc2tm299976(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Wwc2tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |