Cisd1 | CDGSH iron sulfur domain 1

GeneMGI:1261855Synonyms: mitoNEET, D10Ertd214e, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean platelet volume1 supporting datasetCisd1em1(IMPC)HmguhomozygoteEarly adult3.55x10-5 
increased circulating chloride level1 supporting datasetCisd1em1(IMPC)HmguhomozygoteEarly adult4.52x10-6 
decreased circulating triglyceride level1 supporting datasetCisd1em1(IMPC)HmguhomozygoteEarly adult6.32x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cisd1em1(IMPC)HmguExon Deletionmouse
Cisd1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cisd1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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