Vrk1 | vaccinia related kinase 1

GeneMGI:1261847Synonyms: 51PK

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased thigmotaxis	2 supporting datasets	Vrk1^em1(IMPC)Mbp	heterozygote	Early adult	2.36x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Vrk1^em1(IMPC)Mbp	heterozygote	Early adult	8.5x10^-5
embryonic lethality prior to tooth bud stage	1 supporting dataset	Vrk1^em1(IMPC)Mbp	homozygote	E12.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Vrk1^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Vrk1^em1(IMPC)Mbp	heterozygote	Early adult	5.94x10^-7
abnormal behavior	1 supporting dataset	Vrk1^em1(IMPC)Mbp	heterozygote	Early adult	2.56x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Vrk1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Vrk1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Vrk1.

IMPC related publications

Loading...

External links

No external links available for Vrk1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Vrk1^em1(IMPC)Mbp*	Indel	‌	mouse
*Vrk1^{em1(IMPC)Wtsi}*	Point Mutation	‌	mouse

My Genes