Wnt2b | wingless-type MMTV integration site family, member 2B

GeneMGI:1261834Synonyms: Wnt13

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

irregularly shaped pupil1 supporting datasetWnt2btm1b(EUCOMM)WtsihomozygoteEarly adult2.89x10-5 
enlarged spleen1 supporting datasetWnt2btm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetWnt2btm1b(EUCOMM)WtsihomozygoteEarly adult8.37x10-6 
enlarged kidney1 supporting datasetWnt2btm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsWnt2btm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
small spleen1 supporting datasetWnt2btm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetWnt2btm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wnt2btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Wnt2btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Wnt2btm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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