Myo15a | myosin XVA

GeneMGI:1261811Synonyms: Myo15

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



absent pinna reflex	1 supporting dataset	Myo15a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.05x10^-18
abnormal lens morphology	1 supporting dataset	Myo15a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.26x10^-6
increased total body fat amount	1 supporting dataset	Myo15a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.63x10^-5
increased grip strength	2 supporting datasets	Myo15a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.39x10^-6
cataract	1 supporting dataset	Myo15a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.26x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Myo15a.

Associated images

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Histopathology

There is no histopathology data found for Myo15a.

IMPC related publications

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External links

No external links available for Myo15a.

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*Myo15a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Myo15a^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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