Cyria | CYFIP related Rac1 interactor A

GeneMGI:1261783Synonyms: Fam49a, D12Ertd553e, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Cardiovascular system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating creatinine level1 supporting datasetCyriaem1(IMPC)HmguhomozygoteEarly adult2.29x10-5 
abnormal retina blood vessel morphology2 supporting datasetsCyriaem1(IMPC)HmguhomozygoteEarly adult3.64x10-5 
abnormal retina morphology1 supporting datasetCyriaem1(IMPC)HmguhomozygoteEarly adult2.12x10-5 
abnormal retina vasculature morphology1 supporting datasetCyriaem1(IMPC)HmguhomozygoteEarly adult1.52x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cyriaem1(IMPC)HmguExon Deletionmouse
Cyriatm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cyriatm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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