Atg14 | autophagy related 14

GeneMGI:1261775Synonyms: D14Ertd436e, D14Ertd114e, +1 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Integument Vision/eye Mortality/aging

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



persistence of hyaloid vascular system	1 supporting dataset	Atg14^em1(IMPC)Mbp	heterozygote	Early adult	8.05x10^-9
enlarged testis	1 supporting dataset	Atg14^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Atg14^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Atg14^em1(IMPC)Mbp	heterozygote	Early adult	6.35x10^-5
abnormal skin morphology	1 supporting dataset	Atg14^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Atg14^em1(IMPC)Mbp	heterozygote	Early adult	5.99x10^-5
abnormal testis morphology	1 supporting dataset	Atg14^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atg14.

Associated images

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Histopathology

There is no histopathology data found for Atg14.

IMPC related publications

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External links

No external links available for Atg14.

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*Atg14^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Atg14^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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