Endog | endonuclease G

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Pigmentation Integument Endocrine/exocrine gland

17 No significant impact

3 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation1 supporting datasetEndogtm1.1(KOMP)VlcghomozygoteEarly adult6.77x10-5 
small testis1 supporting datasetEndogtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetEndogtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsEndogtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Endogtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Endogtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Endogtm413102(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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