Sgpl1 | sphingosine phosphate lyase 1

GeneMGI:1261415Synonyms: D10Xrf456

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Mortality/aging

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Sgpl1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Sgpl1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Sgpl1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Sgpl1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Sgpl1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sgpl1.

Associated images

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Histopathology

There is no histopathology data found for Sgpl1.

IMPC related publications

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External links

No external links available for Sgpl1.

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*Sgpl1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Sgpl1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Sgpl1^{tm87163(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes