Bap1 | Brca1 associated protein 1

GeneMGI:1206586Synonyms: 2300006C11Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Integument Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton Mortality/aging

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



increased basophil cell number	2 supporting datasets	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	8.85x10^-19
abnormal auditory brainstem response	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	8.75x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Bap1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal vibrissa morphology	1 supporting dataset	Bap1^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	6.41x10^-6
increased eosinophil cell number	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	1.39x10^-6
abnormal vocalization	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	3.55x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Bap1^{em2(IMPC)Marc}	homozygote	Early adult	N/A ^*
abnormal bone structure	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	1.75x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bap1.

Associated images

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Histopathology

There is no histopathology data found for Bap1.

IMPC related publications

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External links

No external links available for Bap1.

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*Bap1^{em2(IMPC)Marc}*	Deletion	‌	mouse
*Bap1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Bap1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bap1^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Bap1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Bap1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Bap1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bap1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Bap1^{tm78193(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Bap1^{tm78193(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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