Bap1 | Brca1 associated protein 1

GeneMGI:1206586Synonyms: 2300006C11Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Integument Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton Mortality/aging

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



increased basophil cell number	2 supporting datasets	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	8.85x10^-19
abnormal auditory brainstem response	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	8.75x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Bap1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal vibrissa morphology	1 supporting dataset	Bap1^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	6.41x10^-6
increased eosinophil cell number	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	1.39x10^-6
abnormal vocalization	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	3.55x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Bap1^{em2(IMPC)Marc}	homozygote	Early adult	N/A ^*
abnormal bone structure	1 supporting dataset	Bap1^{em2(IMPC)Marc}	heterozygote	Early adult	1.75x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Bap1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Bap1.

IMPC related publications

Loading...

External links

No external links available for Bap1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Bap1^{em2(IMPC)Marc}*	Deletion	‌	mouse
*Bap1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Bap1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Bap1^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Bap1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Bap1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Bap1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Bap1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Bap1^{tm78193(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Bap1^{tm78193(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes