Vps26c | VPS26 endosomal protein sorting factor C

GeneMGI:1206040Synonyms: Dcra, Dscr3, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Pigmentation Integument Vision/eye Liver/biliary system Behavior/neurological Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

prenatal lethality1 supporting datasetVps26cem1(IMPC)JhomozygoteE18.5N/A * 
absent vibrissae1 supporting datasetVps26cem1(IMPC)JheterozygoteEarly adult3.28x10-5 
microphthalmia1 supporting datasetVps26cem1(IMPC)JhomozygoteE12.5N/A * 
abnormal cornea morphology1 supporting datasetVps26cem1(IMPC)JheterozygoteEarly adult1.95x10-6 
abnormal locomotor behavior1 supporting datasetVps26cem1(IMPC)JheterozygoteEarly adult8.56x10-6 
pale liver1 supporting datasetVps26cem1(IMPC)JhomozygoteE12.5N/A * 
abnormal coat/hair pigmentation1 supporting datasetVps26cem1(IMPC)JheterozygoteEarly adult4.46x10-15 
preweaning lethality, complete penetrance1 supporting datasetVps26cem1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Vps26cem1(IMPC)JExon Deletionmouse
Vps26ctm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Vps26ctm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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