Slc16a2 | solute carrier family 16 (monocarboxylic acid transporters), member 2

GeneMGI:1203732Synonyms: XPCT, MCT8

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Cardiovascular system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:90Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased heart weight	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.76x10^-6
increased circulating amylase level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.42x10^-9
increased heart weight	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	hemizygote	Early adult	4.76x10^-6
decreased circulating HDL cholesterol level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	hemizygote	Early adult	1.03x10^-5
decreased circulating cholesterol level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	hemizygote	Early adult	6.03x10^-7
decreased circulating creatinine level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.97x10^-6
increased circulating magnesium level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.21x10^-6
decreased circulating fructosamine level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.97x10^-5
increased circulating calcium level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.27x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Slc16a2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.77x10^-42

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc16a2.

Associated images

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Histopathology

There is no histopathology data found for Slc16a2.

IMPC related publications

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External links

No external links available for Slc16a2.

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*Slc16a2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Slc16a2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc16a2^{tm1c(KOMP)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Slc16a2^{tm1d(KOMP)Wtsi}*	Deletion allele (post-Flp and Cre with no reporter)	‌	mouse
*Slc16a2^{tm296790(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Slc16a2^{tm41111(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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