Pik3c2a | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| increased neutrophil cell number | 2 supporting datasets | Pik3c2atm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.31x10-14 | ||
| embryonic growth retardation | 1 supporting dataset | Pik3c2atm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Pik3c2atm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.77x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Pik3c2atm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Pik3c2atm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Pik3c2atm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Pik3c2atm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| decreased lymphocyte cell number | 1 supporting dataset | Pik3c2atm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.67x10-6 |
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External links
No external links available for Pik3c2a.
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| Pik3c2atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pik3c2atm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pik3c2atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |