Angpt2 | angiopoietin 2

GeneMGI:1202890Synonyms: Ang2, Ang-2

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Angpt2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Angpt2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Angpt2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Angpt2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small thymus	1 supporting dataset	Angpt2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Angpt2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Angpt2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Angpt2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Angpt2.

Associated images

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Histopathology

There is no histopathology data found for Angpt2.

IMPC related publications

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External links

No external links available for Angpt2.

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*Angpt2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Angpt2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Angpt2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Angpt2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Angpt2^{tm92002(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Angpt2^{tm92002(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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