Btf3 | basic transcription factor 3

GeneMGI:1202875Synonyms: 1700054E11Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Renal/urinary system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased mean corpuscular volume	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	3.96x10^-13
decreased lymphocyte cell number	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	8x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	2.18x10^-7
abnormal eye morphology	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	2 supporting datasets	Btf3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased leukocyte cell number	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	9.78x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Btf3^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
enlarged urinary bladder	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Btf3^em1(IMPC)Tcp	heterozygote	Early adult	7.83x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Btf3.

Associated images

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Histopathology

There is no histopathology data found for Btf3.

IMPC related publications

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External links

No external links available for Btf3.

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*Btf3^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Btf3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Btf3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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