Tcf21 | transcription factor 21

GeneMGI:1202715Synonyms: Pod1, capsulin, +5 more

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Embryo Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Cardiovascular system Renal/urinary system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



anophthalmia	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Tcf21^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Tcf21^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Tcf21^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Tcf21^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tcf21.

Associated images

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Histopathology

There is no histopathology data found for Tcf21.

IMPC related publications

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External links

No external links available for Tcf21.

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*Tcf21^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Tcf21^{tm417684(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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