Supt5 | suppressor of Ty 5, DSIF elongation factor subunit

GeneMGI:1202400Synonyms: Supt5h, Spt5

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Skeleton Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

vertebral transformation1 supporting datasetSupt5tm2a(KOMP)WtsiheterozygoteEarly adult4.61x10-6 
preweaning lethality, complete penetrance1 supporting datasetSupt5tm2a(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Supt5tm192872(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Supt5tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Supt5tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Supt5tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Supt5tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Supt5tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Supt5tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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