Mmp8 | matrix metallopeptidase 8

GeneMGI:1202395Synonyms: Collagenase-2

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



decreased circulating free fatty acids level	1 supporting dataset	Mmp8^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.58x10^-5
increased heart weight	1 supporting dataset	Mmp8^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.84x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mmp8.

Associated images

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Histopathology

There is no histopathology data found for Mmp8.

IMPC related publications

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External links

No external links available for Mmp8.

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*Mmp8^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Mmp8^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Mmp8^{tm209418(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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