Cxadr | coxsackie virus and adenovirus receptor

GeneMGI:1201679Synonyms: MCVADR, MCAR, +2 more

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Immune system Embryo Growth/size/body region Digestive/alimentary Nervous system Liver/biliary system Hematopoietic system Cardiovascular system Mortality/aging Renal/urinary system

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal spleen morphology	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal stomach morphology	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Cxadr^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal neural tube morphology	1 supporting dataset	Cxadr^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
small spleen	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal placenta morphology	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
small kidney	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Cxadr^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Cxadr^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cxadr.

Associated images

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Histopathology

There is no histopathology data found for Cxadr.

IMPC related publications

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External links

No external links available for Cxadr.

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*Cxadr^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Cxadr^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cxadr^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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