Cacna1g | calcium channel, voltage-dependent, T type, alpha 1G subunit

GeneMGI:1201678Synonyms: a1G, Cav3.1d

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Renal/urinary system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged kidney1 supporting datasetCacna1gem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetCacna1gem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsCacna1gem1(IMPC)MbphomozygoteEarly adultN/A * 
increased exploration in new environment1 supporting datasetCacna1gem1(IMPC)MbphomozygoteEarly adult5.92x10-17 
abnormal skin morphology1 supporting datasetCacna1gem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetCacna1gem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetCacna1gem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cacna1gem1(IMPC)MbpExon Deletionmouse
Cacna1gtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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