Ccr8 | C-C motif chemokine receptor 8

GeneMGI:1201402Synonyms: Cmkbr8

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased thigmotaxis	2 supporting datasets	Ccr8^em1(IMPC)Mbp	homozygote	Early adult	5.86x10^-121
abnormal behavior	1 supporting dataset	Ccr8^em1(IMPC)Mbp	homozygote	Early adult	2.13x10^-120
decreased locomotor activity	3 supporting datasets	Ccr8^em1(IMPC)Mbp	homozygote	Early adult	1.26x10^-13
abnormal eye morphology	1 supporting dataset	Ccr8^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased anxiety-related response	1 supporting dataset	Ccr8^em1(IMPC)Mbp	homozygote	Early adult	6.55x10^-134

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccr8.

Associated images

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Histopathology

There is no histopathology data found for Ccr8.

IMPC related publications

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External links

No external links available for Ccr8.

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*Ccr8^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ccr8^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ccr8^{tm373981(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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