Nlk | nemo like kinase

GeneMGI:1201387

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased startle reflex	1 supporting dataset	Nlk^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	2.53x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Nlk^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	4.88x10^-5
abnormal auditory brainstem response	1 supporting dataset	Nlk^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	6.09x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Nlk^{tm2b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Nlk.

Associated images

Loading...

Histopathology

There is no histopathology data found for Nlk.

IMPC related publications

Loading...

External links

No external links available for Nlk.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Nlk^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nlk^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nlk^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nlk^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes